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簡(jiǎn)介：RU 58841是雄激素受體拮抗劑，可促進(jìn)頭發(fā)再生。

RU 58841物理化學(xué)性質(zhì)：

密度	1.4±0.1 g/cm3
沸點(diǎn)	493.6±55.0 °C at 760 mmHg
分子式	C17H18F3N3O3
分子量	369.338
閃點(diǎn)	252.3±31.5 °C
精確質(zhì)量	369.130035
PSA	84.64
LogP	1.39
蒸汽壓	0.0±1.3 mmHg at 25°C
折射率	1.56

RU 58841詳細(xì)介紹：

中文名稱(chēng)：	4-[3-(4-羥基丁基)-4,4-二甲基-2,5-二氧代-1-咪唑烷基]-2-(三氟甲基)苯腈
中文別名：	4-[3-(4-羥基丁基)-4,4-二甲基-2,5-二氧代-1-咪唑烷基]-2-(三氟甲基)苯腈;4-[3-(4-羥基丁基)-4,4-二甲基-2,5-二氧代-1-咪唑啉]-2-(三氟甲基)苯甲腈;治脫發(fā);苯腈, 4-[3-(4-羥基丁基)-4,4-二甲基-2,5-二氧代-1-咪唑烷基]-2-(三氟甲基)-;RU58841
英文名稱(chēng)：	4-(3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile
英文別名：	4-(3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile;4-(4,4-Dimethyl-2,5-dioxo-3-(4-hydroxybutyl)1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile;4-[3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-trifluoromethylbenzonitrile;RU 58841;4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile;RU-58841;RU58841`;4-(4,4-dimethyl-2,5-dioxo-3-(4-hydroxy-butyl)-1-imidazolidinyl)-2-(trifluoromethyl)-benzonitrile;4-[3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile;RU 5884;RU 58841(RU-58841);Benzonitrile, 4-[3-(4-hydroxybutyl)-4,4-diMethyl-2,5-dioxo-1-iMidazolidinyl]-2-(trifluoroMethyl)-;4-(4,4-Dimethyl-2,5-dioxo-3-(4-hydroxybutyl)1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile(RU 58841);4-[3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile RU 58841;RU58841;ARBYGDBJECGMGA-UHFFFAOYSA-N;0D8FJQ0ADW;Benz
CAS號(hào)：	154992-24-2
分子式：	C17H18F3N3O3
分子量：	369.34
詳細(xì)描述：	博飛美科提供154992-24-2，RU 58841，Perfemiker，上?，F(xiàn)貨。 Medlife，致力于提供高品質(zhì)、高性?xún)r(jià)比小分子化合物的產(chǎn)品。 Medlife小分子化合物大量庫(kù)存，提供超過(guò)2萬(wàn)種的抑制劑、激動(dòng)劑、拮抗劑等產(chǎn)品，是藥物及疾病研究的重要原料供應(yīng)商。 RU 58841 (PSK-3841) 是雄激素受體拮抗劑，可促進(jìn)頭發(fā)再生。查詢(xún)關(guān)鍵詞:“154992-24-2，RU 58841，PC10429，Perfemiker，上?，F(xiàn)貨”。

RU 58841參考文獻(xiàn)：

[1]. A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice By De Brouwer, B.; Tetelin, C.; Leroy, T.; Bonfils, A.; Van Neste, D. .From British Journal of Dermatology (1997), 137(5), 699-702.

[2]. Münster U, Nakamura C, Haberland A, Jores K, Mehnert W, Rummel S, Schaller M, Korting HC, Zouboulis ChC, Blume-Peytavi U, Sch?fer-Korting M.RU 58841-myristate--prodrug development for topical treatment of acne and androgenetic alopecia.Pharmazie. 2005 Jan;60(1):8-12.

[3]. Battmann T, Bonfils A, Branche C, Humbert J, Goubet F, Teutsch G, Philibert D.RU 58841, a new specific topical antiandrogen: a candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism.J Steroid Biochem Mol Biol. 1994 Jan;48(1):55-60.

[4]. Blaschke T, Kankate L, Kramer KD.Structure and dynamics of drug-carrier systems as studied by parelectric spectroscopy.Adv Drug Deliv Rev. 2007 Jul 10;59(6):403-10. Epub 2007 May 3.

[5]. Matias JR, Gaillard M.Local inhibition of sebaceous gland growth by topically applied RU 58841.Ann N Y Acad Sci. 1995 Jun 12;761:56-65.