簡介:安乃近,Metamizole sodium是一種非阿片化合物,具有良好的鎮(zhèn)痛、解熱的效果。Metamizole sodium 是一種環(huán)氧合酶-3 (COX-3) 抑制劑。
安乃近物理化學(xué)性質(zhì):
熔點(diǎn) |
187oC |
分子式 |
C13H16N3NaO4S |
分子量 |
333.339 |
精確質(zhì)量 |
333.075928 |
PSA |
95.75 |
LogP |
1.5041 |
外觀性狀 |
白色或淡黃色結(jié)晶粉末 |
儲存條件 |
庫房通風(fēng)低溫干燥 |
穩(wěn)定性 |
Stable. Incompatible with strong oxidizing agents. |
水溶解性 |
水溶性:可溶 |
安乃近詳細(xì)介紹:
中文名稱: |
安乃近 |
中文別名: |
安乃近;[(1,5-二甲基-2-苯基-3-氧代-2,3-二氫-1H-吡唑-4-基)甲氨基]甲烷磺酸鈉鹽 [(2,3-二氫-1,5-二甲基-3-氧-2-苯基-1H-吡唑-4-基)甲氨基]甲烷磺酸鈉;[(2,3-二氫-1,5-二甲基-3-羰基-2-苯基-1H-吡唑-4-基)甲基氨基] 甲磺酸一鈉鹽;((2,3-二氫-1,5-二甲基-3-氧-2-苯基-1H-吡唑-4-基)甲氨基)甲烷磺酸鈉;安乃近 標(biāo)準(zhǔn)品 異丙基硫雜蒽酮混合物;(1,5-二甲基-3-氧代-2-苯基-2,3-二氫-1H-吡唑-4-基)(甲基氨基)甲磺酸鈉鹽;安乃近原藥粉生產(chǎn)廠家生產(chǎn)廠家行情價(jià)格 |
英文名稱: |
Dipyrone |
英文別名: |
Sodium ((1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino)methanesulfonate;ANALGIN;BENZALAGEN;DIPYRONE SODIUM METAMIZOLE;metamizole sodium;METAMIZOL SODIUM;SODIUM [(1,5-DIMETHYL-3-OXO-2-PHENYL-PYRAZOL-4-YL)-METHYL-AMINO]METHANESULFONATE sodium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1h-pyrazol-4-yl)methylamino]methanesulfonate;SODIUM DIPYRONE;sulpyrine;(antipyrinylmethylamino)methanesulfonicacidsodiumsalt (antipyrinylmethylamino)-methanesulfonicacimonosodiumsalt;(antipyrinylmethylamino)-methanesulfonicacisodiumsalt 1-phenyl-2,3-dimethyl-4-methylamino-5-pyrazolon-n-methanesulfonsaeurennatriu;1-phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonatesodium 1-phenyl-2,3-dimethylpyrazolone-(5)-4-methylaminomethanesulfonicacidsodium;4-methylamino-1,5-dimethyl-2-phenyl-3-pyrazolonesodiummethanesulfonate;Dipyrone Metamizole (sodium salt);Alangin;Anador;ARPF;barone;conmel;Dipyron;fevonil;narone;pyretin;pyrojec;Sulpin (1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methylamino)methanesulfonic Acid Sodium Salt Sodium (1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methylamino)methanesulfonate;[ "" ];安乃近;安乃近原藥粉生產(chǎn)廠家生產(chǎn)廠家行情價(jià)格;Methampyrone;Novalgin;Neomelurbrin;Methylmelubrin;Algocalmin;Optalgin;Novalgetol;Sulpyrin;Pyralgin;Novaminsulfone;Novamidazophen;Nevralgina;Pharmalgine Algopyrine;Farmolisina;Noveltex;Feverall;Diprofarn;Keypyrone;Analgine;Dimethone;Alginodia;Paralgin;Metilon;Metapyrin;Gifaril;Bonpyrin;Neo-melubrine;Di-podil;Aminopyrine sodium sulfonate;Novaminsulfonum;Novaminsulfon;Metamizolum natr |
CAS號: |
68-89-3 |
分子式: |
C13N3O4NASH16 |
分子量: |
333.34 |
詳細(xì)描述: |
博飛美科提供68-89-3,安乃近,Metamizole (sodium salt),Perfemiker,上海現(xiàn)貨。 Perfemiker,致力于提供高品質(zhì)、高性價(jià)比小分子化合物的產(chǎn)品。 Perfemiker小分子化合物大量庫存,提供超過2萬種的抑制劑、激動(dòng)劑、拮抗劑等產(chǎn)品,是藥物及疾病研究的重要原料供應(yīng)商。 有解毒、鎮(zhèn)痛、抗風(fēng)濕作用。主要用于退熱,也用于急性關(guān)節(jié)炎、風(fēng)濕性痛、肌肉痛、頭痛等。 查詢關(guān)鍵詞:“68-89-3,安乃近,Metamizole (sodium salt),Perfemiker,上海現(xiàn)貨”。 |
安乃近參考文獻(xiàn):
[1]. A Jasiecka, et al. Pharmacological characteristics of metamizole. Pol J Vet Sci. 2014;17(1):207-14.
[2]. N V Chandrasekharan, et al. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. Proc Natl Acad Sci U S A. 2002 Oct 15; 99(21): 13926–13931.
[3]. Manuela Malsy, et al. Effects of metamizole, MAA, and paracetamol on proliferation, apoptosis, and necrosis in the pancreatic cancer cell lines PaTu 8988 t and Panc-1. BMC Pharmacol Toxicol. 2017 Dec 6;18(1):77.
[4]. Renata Zajaczkowska, et al. Metamizole relieves pain by influencing cytokine levels in dorsal root ganglia in a rat model of neuropathic pain. Pharmacol Rep. 2020 Oct;72(5):1310-1322.