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簡介:脫水穿心蓮內酯,Dehydroandrographolide是從中草藥穿心蓮提取的天然化合物,具有抗感染活性。
脫水穿心蓮內酯物理化學性質:
密度 |
1.2±0.1 g/cm3 |
沸點 |
512.8±50.0 °C at 760 mmHg |
分子式 |
C20H28O4 |
分子量 |
332.43 |
閃點 |
178.3±23.6 °C |
PSA |
86.99 |
LogP |
2.97 |
蒸汽壓 |
0.0±3.0 mmHg at 25°C |
折射率 |
1.584 |
脫水穿心蓮內酯詳細介紹:
中文名稱: |
脫水穿心蓮內酯 |
中文別名: |
脫水穿心蓮內酯;穿心蓮丁素;zzstandard 品牌 脫水穿心蓮內酯對照品;丙二酸二異丙酯;穿心蓮浸膏;穿心蓮內酯;穿心蓮脫水內酯;二氫楊梅素;脫氫穿心蓮內酯(RG);脫水穿心蓮內酯 Dehydroandrographolide;脫水穿心蓮內酯 標準品;脫水穿心蓮內酯(標準品);脫水穿心蓮內酯(穿心蓮丁素);脫水穿心蓮內酯對照品;脫氧野尻霉素;川貝母;穿心蓮總內酯干浸膏,穿心蓮丁素;分析對照品 |
英文名稱: |
Dehydroandrographolide |
英文別名: |
Dehydroandrographolide;ANDROGRAPHOLIDE, DEHYDRO-;14-Deoxy-11-dehydroandrographolide;Dehydroandrographoline;14-(P);DEOXY-11,12-DIDEHYDROANDROGRAPHOLIDE;Dehydroanddrographolide;(3E)-3-[2-[(1S,4aS,5R,6R,8aS)-Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]-2(3H)-furanone;2(3H)-Furanone, 3-[2-[(1S,4aS,5R,6R,8aS)-decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]-, (3E)-;ANDROGRAPHOLIDE, DEHYDRO(RG);Dehydrographkide;6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]-,(3E);ANDROGRAPHOLIDE,DEHYDRO |
CAS號: |
134418-28-3 |
分子式: |
C20H28O4 |
分子量: |
332.43 |
詳細描述: |
博飛美科提供134418-28-3,脫水穿心蓮內酯,Dehydroandrographolide,Perfemiker,上海現(xiàn)貨。 Perfemiker,致力于提供高品質、高性價比小分子化合物的產品。 Perfemiker小分子化合物大量庫存,提供超過2萬種的抑制劑、激動劑、拮抗劑等產品,是藥物及疾病研究的重要原料供應商。 脫水穿心蓮內酯(Dehydroandrographolide)是從中草藥穿心蓮提取的天然化合物,具有抗感染活性。 查詢關鍵詞:“134418-28-3,脫水穿心蓮內酯,Dehydroandrographolide,Perfemiker,上?,F(xiàn)貨”。 |
脫水穿心蓮內酯參考文獻:
[1]. Chen Q, et al. Pharmacokinetics and tolerance of dehydroandrographolide succinate injection after intravenous administration in healthy Chinese volunteers. Acta Pharmacol Sin. 2012 Oct;33(10):1332-6.
[2]. Chao WW, et al. Isolation and identification of bioactive compounds in Andrographis paniculata (Chuanxinlian). Chin Med. 2010 May 13;5:17.
[3]. Basak A, et al. Inhibition of proprotein convertases-1, -7 and furin by diterpines of Andrographis paniculata and their succinoyl esters. Biochem J. 1999 Feb 15;338 ( Pt 1):107-13.
[4]. Zhu T, et al. Dehydroandrographolide succinate inhibits oxidative stress in mice with lipopolysaccharide-induced acute lung injury by inactivating iNOS. Nan Fang Yi Ke Da Xue Xue Bao. 2012 Sep;32(9):1238-41.
[5]. Chen H, et al. Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents. Bioorg Med Chem Lett. 2014 May 15;24(10):2353-9.